In many respects, leadership responsibility for dealing with business disruption is an extension of the shared leadership approach historically applied to tasks such as strategic planning and risk management.
Capsular disruption, with extracapsular extension or absence of a capsule, is associated with poorer prognosis.
Axial a and coronal b T2 images reveal high signal soft-tissue mass involving predominantly the vastus medialis and intermedius with cortical disruption and intraosseous extension at the anteromedial aspect of the right femur (arrow).
We interpret this disruption as resulting from extension and the resulting volcanism between the Bellingshausen and Antarctic plates across a broad, diffuse plate boundary.
This grading system (Table 1) is based on the anatomic extension of disruption of the spleen, as shown on CT scans or during laparotomy.
Homozygous Celsr1 Crsh and Vangl2 Lp mutant embryos do not exhibit developmental delay as assessed by limb development, however, the rostrocaudal axis is markedly shorter due to disruption of axial convergent extension (31, 32).
Any protein/pathway that is important early in life – for development, or reproduction – and is detrimental later, as evidenced by lifespan extension following disruption in adults, may represent a mechanism of antagonistic pleiotropy.
Vacuolation was diffusely present in lesion areas lacking AQP4 and GFAP (Fig. 4d); it was observed only at the peri-vascular areas in early lesions (Fig. 4b) with disintegrated GFAP-positive foot processes, suggesting that the lesions of this model are of vasculocentric origin, with BBB disruption, followed by secondary extension of neutrophil infiltration and tissue vacuolation.
"A year extension posed more disruption to the market as a whole, and would be accompanied by a rate increase," said Anthony Wright, executive director of consumer group Health Access.
Overexpression of PTHrP in myoepithelial cells inhibits ductal extension, but postnatal disruption of the PTHLH gene in these cells has no effect [ 3].
