The failure of DNase I in PBS to have any effect on biofilm disruption is consistent with the requirement of cations for optimum activity of this enzyme.
Therefore, in this setting Mot1 does not appear to apply highly processive sliding of TBP NC2 along DNA but rather utilizes a more direct, local disruption mechanism consistent with previous studies of TBP DNA complexes (Auble and Steggerda, 1999).
It is found that particle acceleration during this current disruption event is consistent with that expected from the development of the cross-field current instability.
This apparent ability to transverse the membrane without disruption is also consistent with CPP-like activity.
As another example, Santangelo and Tornow (1990) showed that the transcription of ADH1 was sensitive to GCR1 disruption, which is consistent with our prediction.
Spectral-domain optical coherence tomography (SD-OCT) imaging showed distortion of foveal contour and a break in Bruch's membrane with disruption of overlying photoreceptors consistent with choroidal neovascularization (Fig. 2a).
We show that the classification of tract segments was consistent with disruption, oedema or compression.
In MSS colon cancers, loss of ACVR2 correlated with larger tumors, consistent with disruption of activin-induced growth suppression.
The interference model of activator-αCTD complex disruption by Spx is consistent with the observation that free Spx does not bind to DNA [10].
SigA causes a "rounding up" of HEp-2 cells, consistent with disruption of the cytoskeleton, causing a loss in the integrity of the cell monolayer [10].
