Sentence examples for disruption and release from inspiring English sources

Nonetheless, we found that HMDM and J774A.1 cell death was dependent on YopJ/YopP expression as indicated by severe membrane disruption and release of cytosolic components (Fig. 1 and Fig. 2).

Short-circuiting of ionic balance due to MPT results in increased organellar swelling leading to outer membrane disruption and release of pro-apoptotic factors.

Rhabdomyolysis (RM) is a clinical syndrome characterized by injury to skeletal muscle fibers with disruption and release of their contents into the circulation.

Uptake of NPs by toxin-coated tumor cells leads to coendocytic uptake of particles with cell-bound toxin; the particles trigger endosome disruption and release of the toxin for tumor cell killing.

Necrosis is cell death in response to external factors, characterized by cell clumping and swelling (C4-2B cells are clumped and swollen at 48−72-h 48−72-h treatment in Figure 1b), protein denaturation, nuclear membrane, organelle, and plaSIM+METbrane disruptreatment release of cellular materinl into extracellular space.

Monocyte inflammatory products released during sepsis, especially TNFα, have been shown to impair skeletal muscle contractility through an increase in mitochondrial or cytosolic production of reactive oxygen species (ROS) [ 18], and calcium-activated calpains lead to Z disk disruption and release of myofilaments, a phenomenon that has been shown to be up regulated in sepsis [ 18].

The degree of cell membrane disruption and nucleus release can be monitored under microscope.

Cycling and reaction conditions were kept identical except for the initial denaturation, which was extended to 3 min to facilitate cell disruption and DNA release.

The optimization of the high pressure homogenizer cell disruption process was carried out to find the optimal values of independent factors (number of passes, cell concentration, and pulse pressure), which provides efficient cell disruption and maximum release of HBsAg.

Overall, sorafenib not only decreased the number of viable cells and inhibited the cell cycle progression of thyroid carcinoma cells from all histological derivations, but caused apoptotic cell death with DNA fragmentation, caspase activation, cell membrane disruption and LDH release.

Parameter variables mainly number of passes, biomass concentration and pulse pressure are primary concerns that would affect the outcome of P. pastoris cell disruption and the release of HBsAg specific protein.