Sentence examples for disruption and expression from inspiring English sources

Fragments used for gene disruption and expression experiments are shown below the genes.

We present an approach based on Boolean analysis to reconstruct a set of parsimonious networks from gene disruption and over expression data.

Moreover, the persistence of astrocyte-enhanced proliferation and immaturity [ 23, 24] several weeks after GA-injection may further sustain a cascade of pathological events responsible for BBB disruption and altered expression of key components of the neurovascular unit.

Gene disruption and over-expression studies have so far failed to reveal any biochemical or cellular roles for these proteins.

However, the saponin-degrading tomatinase from F. oxysporum f. sp. lycopersici has recently been confirmed as a virulence factor in tomato, by targeted disruption and over-expression of the corresponding gene [ 56].

To construct LA-producing strains, the ethanol fermentation pathway of K. marxianus was redirected to LA production by disruption of KmPDC1 and expression of l- and d-lactate dehydrogenase (LDH) genes derived from Lactobacillus plantarum under the control of the K. marxianus translation elongation factor 1α promoter.

Several vectors for disruption of OCH1 and expression of different glycosidases or glycosyltransferases are available to achieve mammalian-type N-glycan structures in P. pastoris.

Groups of animals are often large in modern poultry breeding conditions, resulting in repeated group disruption and encouraging the expression of aggressive behaviors [ 1].

We found that this specific subset of miRNAs was down-regulated during senescence due to miRNA disruption, and the forced expression of miR-93 could overcome DGCR8-mediated senescence.

Disruption of the function and expression of G9a and EZH2 by their respective inhibitors and siRNAs resulted in marked reductions in H3K9me3 and H3K27me3 and in DNA methylation at the COX-2 promoter and led to the restoration of COX-2 expression and PGE2 production.

In contrast, the amplified developmental instability hypothesis suggests that the dosage imbalance of genes on HSA21 results in a general disruption of genomic regulation and expression of genes involved in development, which upsets normal homeostasis and results in many of the traits associated with DS [ 9].