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A considerable number of experiments performed in vitro have shown that Treg cells depend on direct cell-cell contact to mediate their inhibitory activity, and have suggested that the major mechanisms described (inhibitory cytokines, cytolysis and metabolic disruption) act directly on the effector T cell (reviewed in[8]).
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Disruption acted as means to get to know how the house works and thus affected the competence of the dwellers.
As suggested by Hale and Kalisz (2012), chronic RFS-mutualism disruption could act as the first step in native plant biodiversity loss.
However, ecologic disruption may act as an indirect or partial determinant even for some of these infections (e.g., as in the case of cholera transmission; Tauxe et al. 1994).
Thus, the present study has shown that circadian disruptions can act as environmental stressors to influence genetic risk.
Although, the role of WIF-1 and DKK3 in the Wnt-signaling pathway is still poorly understood, these data may suggest that methylation of these Wnt-antagonists is complementing APC disruption and acts synergistically [ 11, 38].
The second category of risks may arise from natural disasters, strikes and economic disruptions, terroristic acts, and etc.
High Disruption is the act of directing a premium product or service at today's affluent customers.
The data reveal two steps in which PBDK sphing may act: (i) disruption of N36 assembly, and (ii) subsequently the disruption of gp41 core formation.
What is really difficult and tricky about the disruption debate is the act of distinguishing disruption, and acting and thinking as if it (disruption) can exist without its opposite (stability).
The Affordable Care Act "represents disruption," said Kevin J. Counihan, who spent several years in Massachusetts helping to run its marketplace before coming to Connecticut to head its exchange.
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