Sentence examples for disrupting the function of from inspiring English sources

Fusions may drive oncogenic growth by joining a proliferation-inducing gene to an active promoter, by disrupting the function of tumor suppressor genes, or by creating novel functional products that rewire the biochemical pathways that regulate cellular division [ 1].

Disrupting the function of our nervous system can lead to devastating consequences.

We have identified the first naturally occurring mutations disrupting the function of the human Jak3 kinase domain.

In a broader perspective, our findings demonstrate that plastic nanoparticles are transferred up through a food chain, enter the brain of the top consumer and affect its behaviour, thereby severely disrupting the function of natural ecosystems.

Enzymes can stitch the dangling ends back together, which often results in one or more bases – the building blocks of DNA – being added or deleted, disrupting the function of the gene.

His thesis was titled "Acutely disrupting the function of PirB enhances ocular dominance plasticity". This summer, he is continuing his research to determine whether pharmacologically blocking PirB can rescue plasticity in disease models.

Phthalates have been linked to disrupting the functioning of the endocrine system, which controls growth and development in children.

Oxidants may also confer susceptibility to other pathogenic processes by disrupting the functions of cytoprotective proteins, such as metabolic enzymes and cell membrane transporters [7].

To this, one could add (v) any drug disrupting the functioning of the target also abolishes the effect of GAs.

The abnormal gene is able to disrupt the function of the normal gene, causing disease.

All mutations, either in a homozygous or compound-heterozygous state, disrupted the function of the gene.