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Fusions may drive oncogenic growth by joining a proliferation-inducing gene to an active promoter, by disrupting the function of tumor suppressor genes, or by creating novel functional products that rewire the biochemical pathways that regulate cellular division [ 1].
She is a "glitch", and therefore a hazard to herself and the game's future, as she regularly fritzes into clumps of code disrupting the function of those around her.In real life, the internet multiplayer video-game named "Glitch" has faced its own popularity contest and lost.
Disrupting the function of our nervous system can lead to devastating consequences.
We have identified the first naturally occurring mutations disrupting the function of the human Jak3 kinase domain.
However, the situation reverses at E15, when disrupting the function of CD44 at the chiasm sharply reduced ipsilateral projections but the contralateral projections are normal (Lin and Chan, 2003).
Lily Fu Claffee, a partner at Jones Day who served as deputy general counsel in the Paulson Treasury Department, also cautions, "When you're trying to assemble an agency from the pieces of other agencies, you risk disrupting the function of the agency you took the power from".
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However, the contact pressure magnitude and distribution are difficult to measure experimentally without disrupting the functioning of the articulation.
Phthalates have been linked to disrupting the functioning of the endocrine system, which controls growth and development in children.
Oxidants may also confer susceptibility to other pathogenic processes by disrupting the functions of cytoprotective proteins, such as metabolic enzymes and cell membrane transporters [7].
Thermal fluctuations can lead to significant, unpredictable concentration changes in intracellular molecules, potentially disrupting the functioning of cellular networks and challenging cellular efficiency.
To this, one could add (v) any drug disrupting the functioning of the target also abolishes the effect of GAs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com