Sentence examples for disrupting the expression from inspiring English sources

In Drosophila, disrupting the expression levels of chico, a mammalian IRS homology, resulted in enhanced immune function, improved behavior, and extended lifespan (Martin and Grotewiel, 2006; Libert et al., 2008).

Dale's team is also looking at how gene insertion itself may alter transgenic plants, for example by disrupting the expression of endogenous plant genes close to the location of the insertion.

We then investigated the role of ACSL4 and ACOT2 in the production of lipooxygenase metabolites by disrupting the expression of endogenous ACSL4 and ACOT2 in MDA-MB-231 breast cancer cells.

Previous results indicate that pharmacological blockade of spontaneous electrical activity alters the normal pattern of motor axon guidance by disrupting the expression of specific guidance molecules in the chicken [3], [15].

All three classes of small RNAs are known to be implicated in RNA degradation pathways, thus disrupting the expression of endogenous genes (miRNAs and siRNAs), as well as in the control of transposable elements (siRNAs and piRNAs) [9], [10], [11].

Taken together, these data suggest that disrupting the expression of Hif-1α increases the sensitivity of bone to intermittent PTH.

Both regimens of E2 disrupted the expression of spatial memory in place-learners following the novel start position.

Gene fusions in cancer typically lead to the expression of a fusion protein or disrupt the expression of one of the parental genes.

This so-called microRNA disrupts the expression of two key cellular genes called TGF-β and SMAD3, in a process known as RNA interference (RNAi).

Our data indicated that in Japanese rice fish, ethanol disrupted the expression of only cnr1a in a concentration-dependent manner that induced delay in hatching and might be responsible for the development of FASD phenotypes.

After selection with puromycin (0.5 µg/mL) for 2 days, FACS was performed to analyze the expression levels of the dual fluorescence markers, which showed that NLS-TALENs were highly efficient in targeting nuclear sequences and disrupted the expression of EGFP in 13%20%% of the transfected cells.