As a fashion brand, you are selling to the high street and to high-end – you have to protect the top end of your brand so you can sell other items at the lower end – so offending your key market and key fans, icons of fashion and a patrician of gay culture in Elton John, presents a disrupted point of view in PR terms.
The match featured a strange moment when a spare ball fell out of Mónaco's pocket and disrupted a point.
Revel Systems — The aim here is to completely disrupt the point of sale idea for restaurants and retail.
This key Apple hire is perhaps the strongest public signal yet of Apple's intent to use NFC to build on its micropayments franchise and disrupt traditional point of sale using a mobile commerce model.
As Grazer wrote in his book, A Curious Mind, the entire meeting "completely disrupted" his point of view.
These properties were examined in a monolayer wound healing response, comparing MEFs expressing WT p130Cas versus variants in which the signaling capacities of the SD and/or the SBD were disrupted by point mutations.
For example, secondary structure elements in group II introns disrupted by point mutations could be stabilized by the interaction with PPR proteins.
Though Chris Paul is an excellent defender, the Clippers don't want him burning up too much energy on that end, and Bledsoe has proved capable of thoroughly disrupting the opposing point guard.
Finally, we show with disrupting and stabilizing point mutations in the IRES sequence that the software-predicted secondary structure is likely to be correct and functional with regard to the IRES activity.
To determine whether essential Sgt1 functions in yeast are also dependent on its interaction with Hsp90, we engineered similar interface-disrupting point mutations, singly and in combination, into yeast Sgt1 and determined their ability to confer viability in the absence of a wild-type Sgt1 allele (see Materials and methods).
