Sentence examples for disrupting its function from inspiring English sources

Many gynecologists refuse to perform salpingectomy at the time of hysterectomy due to blocking uterine blood flow to the ovaries and disrupting its function [11].

This system inserts a kanamycin gene into the gene of interest, thereby disrupting its function.

However, preliminary analysis of the findings studies indicates that IST can be introduced into a busy, antenatal clinic without disrupting its function.

Here, we report the incorporation of a protein tag to the rn gene locus without disrupting its function.

Gene trapping varies from targeted mutagenesis in that a construct carrying a reporter gene can insert into a gene, disrupting its function.

We did not identify any early mutations that could serve as direct targets for therapy, since TP53 is notoriously difficult to target in cancer cells without disrupting its function in normal cells.

In cervical Carcinogenesis, the HPV E7 protein binds to cellular pRB, disrupting its functions and altering cell cycle regulatory pathways.

14 Etravirine, as other NNRTI, is a noncompetitive inhibitor of the HIV RT enzyme; by binding to the hydrophobic pocket proximal to the active site, it causes a conformational change in the enzyme and disrupts its function.

It is possible that a GFP tag on LARP-5 disrupts its function.

Homozygous mutations in human PTF1A that disrupt its function or expression cause pancreatic agenesis, supporting its role in pancreas development (Sellick et al., 2004; Weedon et al., 2014).

However, the metabolism of some drugs and compounds leads to toxic intermediates that can harm the liver and severely disrupt its function [ 2].