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This is because there are in general many more ways of disrupting function than enhancing it, and many of the ways of disrupting function are not particularly informative.
However, some proteins can be challenging to fragment without disrupting function, such as near-infrared fluorescent protein (IFP).
That is, disrupting function in the right cerebellum selectively impaired the prediction aspect of sentence processing in this task; other language processes were spared.
The present study is a specific example of the more general effects of disrupting function in one part of a complex system on activation in remote areas.
Mutations disrupting function of either cis-acting RNA elements or trans-acting RNA binding proteins (RBP) form the basis for many heritable human diseases [ 3- 5].
The strength of the predictions is proportional to that of the related experimental effect (23, 34), so variants disrupting function on several levels were more accurately predicted (function count; see Results).
Similar(50)
Antibiotics typically work by disrupting functions that are essential to the survival of bacterial cells.
When KillerRed is fused to a protein of interest, it usually disrupts function and localization of other proteins due to its larger size and functional dimerization.
The study, supported in part by N.I.H., involved telomeres — structures on the ends of chromosomes that shorten with age, causing disrupted function of the chromosomes.
What is most striking about their finding is the relation between disrupted function and self-feeling.
Injuries to their avascular inner regions do not heal, disrupt function, and increase the risk for knee osteoarthritis.
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