Secondly, we wished to examine whether there are disrupted top-down influences from inferior frontal gyrus or bottom-up influences from fusiform gyrus in reading disability.
The disrupted top-down control of algae frequently observed after nutrient addition, especially with predators present (e.g. [25]), did not occur.
Eliminated OFC activity may result in disrupted top-down information processing.
Collaboration threads have always been handled poorly in email systems; CCs and BCCs distort and disrupt top down hierarchies, and flatter organizations are overwhelmed with aggressive copying and information hoarding that begins to look like the rest of what's left: spam.
Taken together, these results suggest that frontal damage may contribute to left inattention by disrupting top-down control and resistance to distractors on the ipsilesional side, whereas parietal damage may disrupt the maintenance of stable locations in space across gaze shifts or time.
Alibaba's record-breaking US IPO may give the impression that the company has the e-commerce market in China sewn up, but there are plenty of fast-growing competitors with an eye on disrupting the top dog.
In three of four of our functional modules, the fraction remained higher even when including up to 20% of the top disrupted pathways.
Although underlying molecular mechanisms are poorly understood, dysfunctions in 5-HT reuptake (5-HT transporter, 5-HTT), catabolism (MAO-A), and postsynaptic receptors (5-HT2A and 5-HT2C) are thought to disrupt PFC top-down control over the amygdala, resulting in emotional dysregulation (1,77 83).
"The kids we see were born to substance-abusing women, were exposed to drugs in utero, did not get good prenatal care, had very disrupted lives and on top of that are living with a disease and one that affects the brain.
They have disrupted the market with top talent shipping out great products, through cutting-edge technology and a customer-centric approach.
These results suggest that the analysis of top ranked disrupted pathways may allow stratification of cancers at the pathway level, which could have prognostic value and possibly aid in diagnosis and treatment decisions.
