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Primers designed for the detection of adeSRABC detected the presence of ISAba16, which disrupted the adeR gene in strain Ab12M, and ISAba1, which disrupted the same gene in strains Ab18 and Ab209.
It exposed the many ways health care was broken and recommended numerous ways it can be systematized and disrupted the same way mainframes gave way to PCs and now iPhones.
The only events that disrupted the same genes in two tumors were translocations t(11 13)(q22.3,q12.11), which breakpoints were located within the genes SKA3 and DDX10.
From root and leaf tissues of hydroponically grown plants, disrupted the same way as for the ACC content, RNA was extracted using the RNAqueous® Phenol-free total RNA Isolation Kit Ambion, Life Technologiess, Paisley, UK), according to the manufacturers instructions.
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To prevent Monday holidays from always disrupting the same classes, the school ignores the day of the week, and rotates, instead, through Day 1, Day 2, Day 3, Day 4 and Day 5, which comes in four variants: Day 5a, 5b, 5c, and 5d.
Even with the hundreds of millions of dollars already passing through its platform, and a number of other players also looking to disrupt the same space, Desai believes that it will be some time before the space feels crowded.
The remaining two substitutions are N154D, which disrupts the same N-linked glycosylation sequon as the T156A substitution in the Herfst et al. set, and T315I in the stalk region.
When available, two clones were used to disrupt the same gene to enhance the robustness of the approach.
If T-DNA insertion occurs at random places in the genome, the chances of disrupting the same gene or even different genes which confound the expected RNAi-mediated phenotype in a similar fashion in two independent transformations is extremely small.
Aberrant acetylation of histones, in particular hypoacetylation, is thought to influence the pathobiology of melanoma by disrupting the same pathways as are affected by mutations and CpG island hypermethylation.
These clinical differences are intriguing, given that both 458dupA and 460dupA disrupt the same restriction site and lead to a shift in the reading frame which lengthens the ferritin light polypeptide by four residues.
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