Sentence examples for disrupted the interaction from inspiring English sources

Moreover, p53-RELA remained in complex, although STAT3 inhibition had blocked this complex from interacting with GIS and disrupted the interaction between STAT3 and p53-RELA complex.

D577N disrupted the interaction by 30±10percentent, while an interaction disruption of 45 ± 10percentt was observed with a double mutation of D577, 578 N.

In contrast, loss of Hsp70 function disrupted the interaction of VHL with both Hsp70 and TRiC.

This confirmed that the active FPPa-OmoMYC peptide disrupted the interaction between MYC and its binding partner MAX and thus competes with MYC for binding to MAX.

Substitutions of key amino acids in the pre-α1 loop of ZIKV C disrupted the interaction with lipid droplets, indicating that the loop is critical for membrane association.

Deletion of the PHD or RING finger domain of UHRF2 disrupted the interaction between UHRF2 and TIP60.

The deletion of residues 20 44 again disrupted the interactions (Fig. 2F).

In summary, we propose that the S228P mutation disrupted the interactions between the two gated doors of the hydrophobic core in CTD.

Furthermore, PLpro-TM interacts with STING, TRAF3, and TBK1, and disrupts the interaction between the components in STING-TRAF3-TBK1 complex that is required for the activation of IRF3.

Mutation of the CLIP-170 domain in Alf1p disrupts the interaction with alpha-tubulin.

Shi, J. et al. Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer.