Sentence examples for disrupted targeting from inspiring English sources

Consistent with the Dg point mutants, R cells had defects in polarity as revealed by disrupted targeting of β catenin to adherens junctions (Fig. S3).

Alternatively, flatworm parasite redox homeostasis could be disrupted targeting selenium incorporation, for instance by selectively inhibiting platyhelminth selenophosphate synthetase or SECIS-binding protein.

Global activation of a promiscuous kinase is unlikely to be advantageous to the cell and would be expected to disrupt targeting of specific signalling pathways.

The identification of mutations that disrupt targeting without affecting secretion or translocation will facilitate further studies on the importance of LRT for BteA function.

Meanwhile addition of different concentrations of mevastatin revealed that targeting of Rab23 and Rab23-GGCC mutant (0.1 μM mevastatin disrupts targeting) were more sensitive to mevastatin than either Rab23-CVLS or H-Ras (5 μM and 1.6 μM mevastatin disrupt targeting, respectively).

As PDZ domains are known to recruit components of lipid signalling pathways to particular membranes (Montell, 1998; Nemoto and de Camilli, 1999), deletion of the PDZ domain may disrupt targeting of the PTENMMAC1 protein to the plasma membrane (Leslie et al, 2000).

The FBI opened the Behavioral Threat Assessment Center in 2010, using a multidisciplinary approach, including psychiatrists, to help identify and disrupt targeted violence.

Among the recommendations made by the committee in its May 2013 report was that the Australian Security and Intelligence Organisation (Asio) be given new powers to "disrupt" target computers that pose a risk to national security; to monitor the entire network on which a target computer is hosted; to use a "third party" computer as a gateway to access to a suspicious computer or network.

In addition, we are disrupting targeted virulence genes using biolistic transformation and assessing their role in the virulence of C neoformans in rabbit and murine models of cryptococcal disease.

Solebit – Solebit provides unique solutions, which disrupt targeted attacks and malware delivery by blocking data streams containing unauthorized code from penetrating the organization.

Conventional MOs are typically used to constitutively disrupt targeted genes in an organism-wide manner.