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This difference suggests a degree of disrupted integrity of the white matter tract.
We concluded that LMNA E82K mutation in mice, and probably in humans, disrupted integrity and triggered apoptosis and finally resulted in DCM and heart failure.
Previous DTI studies using the same dataset revealed disrupted integrity of the optic radiation [39] and plastic changes in the corticospinal tract [40] of the early blind.
On the other hand, RVLM neurons in animals that did not resume spontaneous circulation after Mev-induced cardiac arrest showed necrotic features that included enlarged nucleus, nuclear or cytoplasmic electron lucency (Fig. 5c), disrupted integrity of nuclear membrane and swollen mitochondria with disarrayed cristae (Fig. 5d).
The presence of milk protein in the nasal turbinates and lungs and accompanying inflammation and infection by P7 indicates disrupted integrity of the physical mechanism that directs food to the esophagus rather than nasopharynx and trachea.
Contingency protocols should be established to deal with spills; disrupted integrity of a large-scale culture system could potentially result in the release of large volumes of toxic material, so design features to minimise the likelihood of spillage such as isolation valves and secondary containment may be pertinent.
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Photo (Japanese Tsunami, 2011) resembles severely disrupted integrities of molecular, cellular and sub-cellular structures of immune and non-immune systems in site-specific cancers.
Using in vitro and in vivo assays, we investigated whether exposure to individual PCB congeners can disrupt integrity of the intestinal epithelium via NOX-mediated disruption of TJ proteins.
Although yeast cells grown on glucose do not rely on respiration and do not utilize mtDNA, mutations may disrupt integrity of mtDNA, so it may be lost.
Disrupted neuronal integrity in frontal regions does fit well into models of addiction and the cognitive deterioration in amphetamine-type stimulant polydrug users.
Furthermore, HAMLET disrupted membrane integrity at neutral pH and physiological conditions, as shown by fluorophore leakage experiments.
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