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Jordanova, A. et al. Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.
Guanidinylated polymers disrupted function of isolated mitochondria more than their lysine-based analogs, but overall toxicity was decreased, likely due to inefficient mitochondrial trafficking.
The study, supported in part by N.I.H., involved telomeres — structures on the ends of chromosomes that shorten with age, causing disrupted function of the chromosomes.
What is most striking about their finding is the relation between disrupted function and self-feeling.
Thus, the disrupted function of interneurons due to loss of inhibitory control and increased stimulation could contribute to the cascade of events that lead to persistent chronic pain.
Disrupted function of collagen X, a major hypertrophic cartilage matrix protein, resulted in skeletal and hematopoietic defects in endochondrally derived tissues.
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When KillerRed is fused to a protein of interest, it usually disrupts function and localization of other proteins due to its larger size and functional dimerization.
Dembinski, H. et al. Predicted disorder-to-order transition mutations in IκBα disrupt function.
Mutations in the MRE sequences of three of these CES that disrupt function in vivo abrogate interactions with the LBC.
Injuries to their avascular inner regions do not heal, disrupt function, and increase the risk for knee osteoarthritis.
These consequences are predicted to disrupt function of SEDLIN/TRAPPC2.
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CEO of Professional Science Editing for Scientists @ prosciediting.com