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An elaboration of this view is that the key variables are the severity and extent of disruption of neural circuits with the extent (number and nature of neuronal circuits disrupted) determining the type of syndrome that results (intellectual disability, autism or schizophrenia etc).
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The mechanisms through which this balance is disrupted determine the characteristics and evolution of the tumour (Sanchez-Beato et al, 2003).
Using a knockout approach, the expression of tumor suppressor genes such as Rb and p53 as well as candidate tumor suppressor genes can be disrupted to determine their tumor-suppressive functions [5], [6].
In fact, the expansion of the maxilla disrupts the occlusion determining a slight forward position of the mandible, improving the sagittal occlusal relationship.
We applied transcranial alternating current stimulation (tACS) – which, with a cross-hemispheric electrode montage (F3 and F4 – International 10 20 EEG system), is able to disrupt brain oscillations to determine if disruption of low frequency oscillation generation during afternoon nap is causally related to disruption in declarative memory consolidation.
Last month, rowdy opposition members disrupted elections intended to determine the party leadership of the province that includes the capital, Harare.
The intact biofilms and the sediments of the disrupted biofilms were then determined by using a modified colorimetric assay previously described by Roslev & King [ 30].
To determine if disrupted sarcomere structure could be accounted for by a kinase requirement for normal maintenance of sarcomeres, we knocked down these 50 kinase-encoding genes acutely in adults.
To determine if disrupted mitochondrial morphology could be attributed to a kinase requirement for maintenance of the mitochondrial network in muscle we knocked down the identified kinase encoding genes acutely in adults.
To study the functions of these interfaces we designed mutations that would disrupt them and determined how the mutations affected assembly and GTP hydrolysis.
In September U.S. President Obama imposed a 35% duty on Chinese tires imported to the U.S. after determining that they disrupted the market.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com