Sentence examples for disrupt the recognition from inspiring English sources

In the seed regions alone, 45 SNVs disrupt the recognition site of the miRNA for its targets.

Conversely, changes at positions in the motif that disrupt the recognition of the binding site by the binding-protein are likely to be deleterious, and therefore removed from the population by purifying selection.

These observations indicated that the T-loop mutations do not significantly affect the binding affinity between C2 and CCR5 mRNA sequence but disrupt the recognition of EGS-CCR5 mRNA complex by RNase P. Thus, EGS C2 may be used as a control for the antisense effect in our experiments in cultured cells (see the following).

Polymorphisms in TLR genes have not yet been described in dogs with SNA, but alteration in these receptors could hamper their function, therefore disrupting the recognition of fungi, eventually leading to fungal escape from immune surveillance.

A variety of mechanisms are responsible for RNAi escape, including single-point mutations (which may disrupt the specific recognition of and binding to the siRNA-binding site), deletion of the target sequence, and transcriptional upregulation [ 102].

Adenosine (5.0 10.0 mg/kg), the selective adenosine A1 receptor agonist 2-chloro-N6-cyclopentyladenosine (CCPA, 0.025 0.05 mg/kg) and the selective adenosine A2A receptor agonist N6-[2- 3,5-dimethoxyphenyl -2- 2-methylphenyl)ethyl]adeN6-[2- 3,5-dimethoxyphenyl -2- 2-methylphenyloute 30 miN6-[2- 3,5-dimethoxyphenyl -2- 2-methylphenylogN6-[2- 3,5-dimethoxyphenyl -2- 2-methylphenyl

Such deletion disrupts the DNA recognition helix and results in a frame-shift of the downstream protein-coding sequence.

Moving the American Embassy to Jerusalem, which they both advocate, would "disrupt the peace process beyond recognition," Mr. Ibish said.

To address the specificity of NBS1 and NBS4 core binding sites we have introduced transversion point mutations to the core cognate elements aiming to disrupt the NKX3.1 homeodomain DNA recognition.

Other herpesviruses also have evolved a variety of mechanisms to disrupt the cell surface display of immune recognition molecules.

Overachievers appear self-motivated, less needy of praise and recognition, while poorly behaved students disrupt the learning environment, frustrating both classmates and teachers.