Sentence examples for disrupt the binding from inspiring English sources
Alibaba 2.1 analysis of ss825679004 predicted it to disrupt the binding sites for three transcription factors [Activating Enhancer Binding Protein-2alpha (AP-2alph), NF-muE1, Specificity Protein-1 (Sp1)] and to create a new one for a different transcription factor [GC Factor (GCF)].
R2 disrupted the binding of FAK and p53 in a dose-dependent manner, while the negative control compound (A18),[ 32] which did not bind the FAK-p53 region did not disrupt the binding of FAK and p53.
Disruption of actin fibers with cytochalasin D (data not shown) did not disrupt the binding of FLNa to the receptor, but both proteins were relocated appearing in aggregates in the cell.
Even though the N-terminal domain of L11 is connected with the mobile L10, it does not bind with the aa-tRNA, and therefore the movement does not disrupt the binding between the aa-tRNA and the GAC.
These pseudoknot fluctuations disrupt the binding site by facilitating fluctuations in the 5′-end of helix P1.
In conclusion, this is the first report of small peptides designed to disrupt the binding of SARS-CoV S protein to ACE2.
This is related to the ability of α-amylase to hydrolyze the internal α-1,4 linkages of polysaccharides that could affect some glycoproteins present in the extracellular space and disrupt the binding-site of XDH/XOD.
This is related to the ability of α-amylase to hydrolyze the internal α-1,4 linkages of polysaccharides that could affect some glycoproteins and disrupt the binding-site of XDH/XOD.
However, as a transcription factor, COUP-TFII might also recruit co-repressors to the complex or disrupt the bindings of Smads to the co-activators such as CBP/P300.
Enoksson, M. et al. Caspase-2 permeabilizes the outer mitochondrial membrane and disrupts the binding of cytochrome c to anionic phospholipids.
Furthermore, we showed that Ser70 phosphorylation of Bcl-2 directly regulates apoptosis by disrupting the binding to and sequestration of the pro-apoptotic protein Bim.
