Sentence examples for disrupt the assembly from inspiring English sources
Subsequently, other groups confirmed this phenomenon, and lack of cytochrome c was found to disrupt the assembly and stability of CI and CIV (Vempati et al., 2009).
This would explain why a single Cys mutation could disrupt the assembly of the multiprotein complex thereby, obliterating secretion.
The evolution of the nervous system required network strategies by which novel binding partners can compete with pre-existing ligands in a manner that does not disrupt the assembly of the post-synaptic complex.
In addition, the titration of BiFC signals could only occur when the cold interaction is strong enough to disrupt the assembly between AbdA and Exd.
Because CCA1 and LHY form homo- and heterodimers in vivo[ 17], truncated proteins may also disrupt the assembly of functional dimers and may act as dominant negative regulators.
Failure to remove such abundant contaminant sequences can disrupt the assembly process (due to the high read depth compared with the nuclear genome) and may result in the production of chimeric and contaminated contigs.
NYAD-1 disrupted the assembly of both immature- and mature-like virus particles in cell-free and cell-based in vitro systems.
These features agree with previous reports that a mutation disrupting TMH1 of NDUFA11 destabilized the entire complex, and that blockof NDUFA11 expression disrupted the assembly of CI, resultingin the accumulation of 550 kDa and 815 kDa CI sub-complexes.
The hRSV F protein facilitates viral fusion, a critical extracellular event that can be targeted for therapeutic intervention by disrupting the assembly of a postfusion 6-helix bundle (6HB) within the hRSV F protein.
In this study we propose that M2 protein can be used as a molecular fabricator without disrupting the assembly of VLPs and while retaining the native structures of HA and NA envelope protein oligomers on the particle surfaces.
These data are consistent with our recent studies in zebrafish showing that knockdown of skNAC significantly disrupted the assembly of thick and thin filaments, but with a weak effect on the M- and Z-lines [30].
