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The leading theory of Alzheimer's is that the disease is caused by deposits of a protein called amyloid that build up in the brain, disrupt nerve function and ultimately kill brain cells.
Drugs that disrupt nerve conduction and transmission or central sensitization, currently the only effective treatments, are only modestly effective for a portion of the patients suffering from neuropathic pain and come with the cost of serious adverse effects.
Injection of the scrambled control siRNA did not disrupt nerve cord development (Fig. 4A, Table 1).
We hypothesize that bone fracture may physically disrupt nerve fibers in bone.
Pyrethroids are neurotoxic pesticides that interact with membrane bound ion channels in neurons and disrupt nerve function.
While searching for genetic mutations that disrupt nerve function in the fruit fly Drosophila, Sandoval et al. spotted mutations in a gene called Marf.
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They are found in ground and surface waters and in the food we eat, and they have been shown to disrupt nerve-cell activity in mammals.
These antibodies can then enter the brain and attack the myelin sheath, disrupting nerve conduction and eventually causing death of the axons.
The disease disrupts nerve signals and impairs movement, coordination, vision, and sometimes thinking.
To detoxify botulism toxin, Simpson mutated the region of the protein that disrupts nerve function, leaving the remainder intact.
Like morphine and other narcotics, a painkiller called fentanyl disrupts nerve cells deep in the brain that register pain as well as other cells that govern breathing rhythm.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com