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Such cell cycle disruption is associated with genomic instability, due to mutations and chromosomal aberrations that disrupt critical housekeeping functions, including DNA repair and cell cycle checkpoints.
She said the research, published in Current Biology on Thursday, is "the first clear example, supported by long-term data, of the potential for climate change to disrupt critical [pollination] relationships between species".
The Bush administration is considering the creation of a secure new government communications network separate from the Internet that would be less vulnerable to attack and efforts to disrupt critical federal activities.
[C2.] Bush Seeks Safer Communications The Bush administration is considering creation of a secure government communications network separate from the Internet that would be less vulnerable to cyber-attacks and efforts to disrupt critical federal activities.
It is the lighter-than-air gas that makes a party balloon float up to the ceiling, but a shortage of the element is threatening to disrupt critical research projects.
The real world, however, is prone to various types of unintentional and intentional interference of technogenic (man-made) origin that can disrupt critical communication systems.
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Significant RNA structure has been found to underlie the entire HCV polyprotein, which would further limit the ability of HCV to mutate without disrupting critical structure-function relationships.
However, we cannot exclude the formal possibility that certain mouse-specific regulatory element(s) is disrupted by the gene trap or that the gene trap insertion disrupted critical spacing between regulatory elements.
The first hypothesis was that small lesions disrupting critical neural pathways might precipitate vascular depression.
Importantly, many of the disease-causing mutations inhibit binding by disrupting critical interface contacts.
These findings suggest that EGCG disrupts critical contacts that are required to maintain SEM1(45-107) and SEM2(49-107) fibrils.
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