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To investigate whether the dynamics of F-actin polymerization were important for the inhibition of inflammasome activation by ATP and PPi, we treated M1 polarized P2X7R−/− macrophages with cytochalasin B (CB) to disrupt coordinated actin cytoskeleton assembly.
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Therefore, CEACAM1 seems to be an attractive receptor for pathogens to infect cells and simultaneously disrupt well coordinated immune responses.
Once all the visions, institutional rules and guidelines are openly and continuously shared, disrupted and coordinated, the benefits of the service ecosystem are more likely to emerge [75].
Clinton told the ABC she believed the email leak was coordinated to disrupt the influence of the Access Hollywood tape.
This firing increase seemed to disrupt the neurons' ability to coordinate into persistent firing patterns; as the paper puts it, "[the blast of noise] generally suppressed the ability for past spiking activity of PFC neurons to predict or modulate these neurons' ongoing activity".
The recent attack suggests that such Kuwaitis could potentially disrupt the kingdom's stability by coordinating with foreign jihadists determined to murder Kuwaiti Shi'ites, in a quest to rid the Arabian Peninsula of "heretics" and "rejectionists".
Certain transition metals might disrupt the cellular donor ligands that coordinate Fe.
Even a short delay could disrupt the project's computerized system, which coordinates cues between images, landscape, sound design and performances.
For histone exchange, SWR1 must disrupt either one or both of these interactions, coordinated with H2A.Z-H2B deposition.
We sought to identify BDM incompatibilities in the nematode Caenorhabditis elegans by looking for genomic regions that disrupt egg laying; a complex, highly regulated, and coordinated phenotype.
We sought these by looking at the disruption of a complex, highly regulated and coordinated, phenotype, egg-laying, and undertook screens for genomic regions that disrupt this process.
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CEO of Professional Science Editing for Scientists @ prosciediting.com