Exact(4)
Additional treatments (amiloride, 5- N-ethyl-N-isopropyl)amiloride (EIPA), phenamil, bafilomycin, 4′,6-diamidino-2-phenylindole (DAPI), high sodium) intended to disrupt alternative routes of Na+ uptake yielded no change in FTR or Jsamm, suggesting the absence of direct competition between Na+ and ammonia for transport.
However, comparatively little of this money has been focused on the $138 billion market opportunity to disrupt alternative financial services in the United States.
In the big picture, Zenefits is out to disrupt alternative to traditional insurance brokers, who generally force their clients to use PDFs and fax machines to manage their health insurance benefits and less-than-stellar administrative services.
Although previous studies have shown that over-expression of CELF1 in skeletal muscle is sufficient to disrupt alternative splicing and muscle phenotype [18], [20], this is the first study to test whether CELF activity is normally required in skeletal muscle by specifically repressing CELF activity.
Similar(56)
Further, we identify a point mutation in an intron adjacent to one alternate splice site that disrupts alternative splicing at all three sites.
Thus, enucleation could interfere with the layout of topographic cues in area 18a by disrupting this alternative pathway.
Mutations that disrupt splicing and/or alternative splicing are reported to be an important source of many human diseases [ 8- 11].
Thousands of leftist demonstrators have tried to disrupt a gathering of Alternative for Germany (AfD), the rightwing populist party already riven by internal rivalries five months before the country's general election.
Heart muscle-specific expression of NLSCELFΔ in MHC-CELFΔ mice has been shown to specifically disrupt cardiac CELF-mediated alternative splicing in vivo and leads to cardiomyopathy, severe cardiac dysfunction, and premature death [21], [22].
However, a number of alternative monocistronic transcripts are the result of alternative splices that disrupt one of the two coding regions.
While the debate about whether the "thin film" alternatives would disrupt the industry played out, some manufacturers combined the best of both technologies into a hybrid cell consisting of a silicon wafer with a thin layer of amorphous silicon that converted a much higher percentage of light than crystalline silicon alone.
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