Trabecular bone disconnection is an independent factor in age-related skeletal failure where real termini (ReTm; rare in youth) may cause weakness disproportionate to tissue loss, yet their structural contribution at vulnerable locations remains uncertain.
4 Moreover, the different forms of obesity, such as the generalised and abdominal variety, merit separate attention, especially for South Asians, who have the propensity to accumulate excess adipose tissue disproportionate to their weights.
Growth is a mixture of skeletal growth – tending to be expressed as increased height; and somatic growth, which may be proportionate (ie, a large child, but with a normal body mass index), or disproportionate (increased soft tissue with a raised body mass index/POWFL).
Conversely, and perhaps surprisingly, we did not observe any significant relationship between circulating levels of the extracellular form of FASN and HIV-related dyslipidemia and lipodystrophy, two conditions in which enhanced endogenous fatty acid synthesis is closely linked to the accumulation of lipids and disproportionate distribution of tissue-associated fats.
First described by Feriz in 1925, macrodystrophia lipomatosa is an unusual form of local hypertrophy, congenital in origin but not hereditary [1, 2, 3], and characterized by proliferation of all mesenchymal elements but with a disproportionate increase in adipose tissue.
72 Separately, p53 knockdown in differentiated murine tissue allowed disproportionate expansion of p53−/− cells.
In addition to the loss of total body weight, disproportionate loss of lean tissue weight is common in patients with cancer [ 10].
Other authors have shown that PFM and DFM occur in spite of tibiofibular fixation due to strong tethering effects of the fibular regenerate and interosseous membrane and due to a disproportionate amount of soft tissue tensioning (Hatzokos et al. 2004, Shyam et al. 2009).
Of all the materials valued in biomedical research, embryonic stem (ES) cells and fetal tissue have gotten disproportionate attention from politicians.
For RASSF1A, the three normal parathyroid samples were endowed with virtually no methylation (2.0%, 3.6% and 3.0% respectively) whereas case SHPT1 was endowed with a methylation density of approximately 30%, suggesting that RASSF1A methylation also can be found in parathyroid tissue with an disproportionate growth pattern, albeit not a tumour per definition.
