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The transcriptional hyperactivity in ESCs is accompanied by disproportionate expression of chromatin-remodeling genes and the general transcription machinery.
The increase in LSK numbers in the presence of Wnt4-producing cells was further translated into a 3-fold increase in the number of colony-forming cells (CFCs), indicating that Wnt4 did not induce a disproportionate expression of Sca1 or cKit on cells that would have no HPC capacity (Fig. 2F).
This finding could, indeed, explain the disproportionate expression profiles of both p53 and Bax proteins observed in the present study.
The disproportionate expression of TTP and HuR, as well as their target CXCR4, is also observed in invasive tumors of breast cancer patients and probably can promote invasion and metastasis toward organs where CXCL12 is highly expressed such as bone, liver and lung.
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We're finally open!") and the somewhat disproportionate expressions of contentment on the face of patrons — not to mention investors — when the Munson finally reopened to big crowds last week, a lesson in comfort food, diner lore and other themes that could have been explored had anyone been nuts enough to greenlight the reality show.
Inclusion of such partly necrotic fragments would result in disproportionate high expression levels of hypoxia-responsive genes, which would appear as outliers above the regression line in the scattergrams.
We find that sex-biased genes do not make a disproportionate contribution to expression variation among females.
Because strains within each panel are isogenic aside of the aneuploidy, the reduced slope for Class 3a genes is indicative of dosage compensation while the elevated slope for Class 3b genes represents a disproportionate increase in expression.
The Foreign Office minister, Alistair Burt, said: "I am deeply concerned by the sentencing of three members of the band Pussy Riot, which can only be considered a disproportionate response to an expression of political belief".
There is thus a disproportionate increase in the expression of MDR1 protein relative to gene copy number in the resistant parasites (Table 1).
Consequently, the few sites of ASHM identified in this study would seem to be having a disproportionate affect on gene expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com