Exact(12)
Structure function relationships are instead probed by side-chains of similar or smaller volume: respective substitution of ValB12 by alanine, threonine, and α-aminobutyric acid leads to activities of 1 ±0.1)%, 13 ±6)%, and 14(±5)% (relative to DKP-insulin) without disproportionate changes in negative cooperativity.
Disproportionate changes in either ventricular or arterial elastance will lead to ventriculoarterial decoupling.
It assumed that changes in inputs would lead to disproportionate changes in outputs.
This novel finding has clinical relevance as it indicates that disproportionate changes may occur involving the proximal hip musculature.
36 Interestingly, the Hbmass– relationship appears to uncouple somewhat following altitude training, with disproportionate changes being reported in Hbmass and.
Specifically, several studies implicate the basal ganglia, or disproportionate changes in basal ganglia volume, in autism [ 30- 36].
Similar(48)
Although brain homogenates from these animals are not infectious in bioassays, these models suggest that a disproportionate change in the physiological function of PrPC is as neurotoxic as the gain of toxic function by PrPSc.
Plasma clearance of paclitaxel exhibits non-linear kinetics, which results in a disproportionate change in plasma concentration and area under the concentration time curve with dose alterations.
While CRS assumes that an increase in inputs will increase outputs in the same proportion, VRS allows for a disproportionate change.
Inconsistent consideration of subjective patient reported outcomes may cause a patient to paradoxically report a change when no change has occurred, or a disproportionate change than that which has actually taken place.
Reductions in fracture risk following bisphosphonate treatment are also frequently disproportionate to changes in bone density [ 19, 20].
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