Sentence examples for disproportionate cell from inspiring English sources

While unsupervised hierarchical clustering revealed a high degree of gene correlation between patient-matched FNA and core biopsies overall, disproportionate cell compositions among biopsy types were shown to result in skewed distributions for certain cell type-specific gene expression patterns.

The essentiality of this endogenous population in protecting the host from disproportionate T cell activation and autoreactive effector cells is underscored both in experimental models and in humans in which the numbers and/or function of Treg are compromised [ 6, 10, 16- 20].

Specifically, the 60 nm SNPs were preferentially endocytosed by cells and, at high doses, caused a disproportionate decrease in cell viability.

And, finally, because the riparian tumor cells competitively exclude the xeric tumor cells from prime habitats, the disproportionate decline of riparian cells from treatment may indirectly benefit the xeric-adapted cancer cells.

The end result may be a disproportionate increase in cells with a suppressive or tolerant rather than a proinflammatory phenotype, resulting in an inability of the host to combat pathogens.

As shown by monitoring of CFSE-labeled CD4 T-cells (Fig. 1D), this disproportionate increase of Treg cells is, at least in part, due to enhanced proliferation of Foxp3+ cells.

This elicits disproportionate production of Treg cells and shifts the cellular balance from effector helper cells towards cells with suppressor function in order to avoid immune system mediated destruction.

Some of the uniformity of predictions – both accurate and erroneous - might be the consequence of disproportionate representation of certain cell types among the tissue samples [ 51] or might arise more directly from close functional relationships among the genes, hence an increased likelihood of coordinate gene expression.

Disruption of beta-catenin in cells positive for CD133 resulted in a gross disruption of crypt architecture and a disproportionate expansion of CD133 cells at the crypt base [ 19].

Previously, we found a disproportionate fraction of progenitor cells in BRCA1 mutation carriers with EGFR overexpression.

Moreover, unlike myc−/− cells, where quantitative and qualitative reductions in Complex I occur in parallel, the functional defects of Complex I in Drp1 cells are disproportionate to the levels documented by BNGE.