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PBPK relies primarily on describing drug disposition in terms of organ distribution, blood flow and metabolic capacity (Fig. 2).
Information regarding transporter-mediated drug disposition in terms of tissue-specific transporter abundance and ontogeny of specific transporter systems is currently limited.
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The wrong move, Vihvelin argues, was then to analyze dispositions in terms of simple counterfactual conditionals, which were then readily open to the sorts of counterexamples adumbrated here.
To begin with there is matter of whether the definition merely provides units in which to measure fitness the way that plainly operational definitions do, by contrast with definitions of dispositions in terms of their occurrent bases.
Figure 1 presents the relationships between these dispositions in terms of how the family carers described movements between them over time.
Against this background, Henrich's model either competes with the existing models, or is a social-learning reformulation of the Bass model, explaining innovators' and imitators' differential dispositions in terms of their differential success biases.
Grush (2007 20099) has proposed a detailed implementation of the disposition theory in terms of neural information processing.
Drug disposition is expressed in terms of the space-averaged drug concentrations in the nonhomogeneous macroscopic compartments.
The RER health authorities removed patient name, exact address, and other potential identifiers from the database provided for this study, to respect national dispositions-by-law in terms of privacy.
Gauthier's discussion in Morals by Agreement is conducted in terms of "dispositions to choose" and specifically of "constrained maximization", the disposition to cooperate with other cooperators even in circumstances where defecting is more advantageous.
Peter Wehner, who held key posts in the last three Republican presidential administrations, declares that they cannot: This is not conservatism either in terms of disposition or governing philosophy.
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