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The treatment plan involved the administration of 5-FU (160 mg/m/day) was continuously infused over 24 hours using a disposable infusion pump (7-day Infuser; Baxter™) and CDDP (3 6 mg/m/day) diluted with normal serine was infused for half an hour.
The effect may be enhanced by the addition of a direct operative site infusion of local anaesthetic delivered by disposable infusion pumps.
The SBS required more equipment e.g. infusion pumps and disposable infusion systems as well as more manpower e.g. to fix technical alarms.
A hypodermic needle with disposable infusion device was inserted in the ventriculus sinister with ligation of that proximal to the aorta ascendens.
The vasculature was flushed with 500 mL 50 U/mL heparinized saline at 37°C and at maximum flow via a disposable infusion device.
A disposable infusion device (Pain Pump II, Stryker, Kalamazoo, MI, USA) was used for continuous infusion with the following settings: ropivacaine 0.2%; bolus: 3 mL; continuous infusion: 4 mL/h; lock-out: 20 minutes.
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A mobile disposable negative-pressure infusion pump (Coopdech Syrinjector, Daiken Medical, Osaka, Japan) primed with a total volume of 120 ml anesthetic (113 ml of 0.2 % ropivacaine, 300 μg of fentanyl, and 2.5 mg of droperidol) was used for continuous epidural infusion at a rate of 5 ml/h starting 10 min after skin incision.
Samples for analysis were collected directly from the RBC (C1) bags external ports, after free flow of the blood component on the infusion disposable set (C2) and after submitted to the studied rate (E), exception made to haptoglobin that was analyzed in C1 and E. Data obtained were analyzed according to mean ± standard deviation, ANOVA and t student tests (p≤0.05).
Total cost treatment reflects the cost of drugs, the cost of all resources expended in patient management such as the cost of disposables for each infusion, the monitoring costs during infusion (salaries of personnel), other hospital expenses, the cost for management of adverse events, the productivity loss, and the traveling cost for patients.
In vitro safety assessment of disposable medical devices, including infusion sets, is usually performed using L-929 mouse keratinocytes.
Oral treatment will reduce the number of in-patient and out-patient hospital visits with their associated medical and nursing administrative costs, avoid the expense of disposables (e.g. infusion equipment, pumps) and decrease the pharmacy workload (Twelves et al, 2001).
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