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Whereas in FT locus there were not significant changes (data not shown), chromatin immunoprecipitation experiments demonstrated that the promoter region of FLC displays increased levels of H3K4me3 in the brm-1 plants compared to WT (Figure 3C).

In line with this notion, overexpressing Ndc80 in mice displays increased levels of Mad2, leading to checkpoint hyperactivation and aneuploidy [ 12].

In an independently generated strain of slc4a11-null mice, the corneal stroma displays increased levels of sodium relative to WT (12).

Obesity, which is associated with increased risk of developing PD [ 100], displays increased levels of proinflammatory cytokines including TNF α, IL-1 β, IL-6, and CCL2, in adipose tissue [ 101– 103], liver [ 104], pancreas [ 105], brain [ 106], and possibly muscle [ 107].

In drought stress conditions, BRL3ox shoots displayed increased levels of the amino acids proline, GABA, and tyrosine.

Cells depleted of ETT displayed increased levels of protein carbonylation (Figure 3a, compare black bars to gray). ET pretreatment protected control but not ETT-depleted cells (Figure 3a).

Compared to cells obtained from control animals, splenic DCs from SDR mice displayed increased levels of MHC I, CD80, and CD44, indicative of an activated phenotype.

MSCs seeded on nanowire surfaces also displayed increased levels of alkaline phosphatase (ALP) after 1, 2, and 3 weeks in culture.

In osteogenic conditions, MSCs cultured on nanofiber scaffolds also displayed increased levels of alkaline phosphatase activity for 3 weeks of culture.

Quantitative receptor autoradiography revealed that post-pubertal NVH lesioned animals display increased levels of [3H]pirenzepine/M1-like and [3H]AFDX-384/M2-like receptor binding sites in the striatum, nucleus accumbens, and in subareas of the dorsal hippocampus.

Mice lacking Reelin (Reln), double-knockouts lacking the VLDL receptor (VLDLR) and ApoE receptor2 (andER2), and mice lacking disabled-1 (displayincreasedcreased levels of phosphorylated tau.