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Lastly, DG C and DG GP exhibited high r values between close markers, displaying a strong decrease with distance, with a faster decrease in C than in GP.
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In accordance with data of caspase-9 inhibition, HeLa cells expressing Gadd45 α siRNA and infected with M90T displayed a strong decrease in caspase-3 activity and a significant reduction of DNA fragmentation.
The two independent IVSmut transgenic lines, in which MIR163 had both 5′ and 3′ splice sites mutated, displayed a strong decrease in miR163 accumulation (16 17% of wt level) associated with a strong decrease in pri-miR163 levels (12 14% of wt level; Fig 2B).
Dendrites that were chosen from plaque-free overview images (>100 µm from plaques, supplementary Figure 1a) did not show spine loss (0.36 ± 0.01 spines/µm, Fig. 1b), but the ones that were in close proximity to plaques (<30 µm from plaques, supplementary Figure 1b) displayed a strong decrease in spine density (0.27 ± 0.02 spines/µm, Fig. 1b).
Immunocytochemistry on cardiac fibroblasts displayed a strong reduction in type I collagen staining in both Aga2 severe cells and ECM (Fig. 2A), and a slight decrease in collagen staining in Aga2 mild cells.
Animal studies demonstrated that resveratrol displays a strong antidiabetic effect, decreasing blood glucose in hyperglycemic rodents [ 143].
Thus, Wfs1/CKO mice displayed a significant increase in immobility in the FST and a strong decrease in sucrose preference after exposure to ARS stress.
The placebo provoked a strong decrease in experienced disgust.
The decreased T4-synthesis was paralleled by a strong decrease of Nis expression.
Instead, we see a strong decrease in nighttime sleep.
It displays a strong up-shift of transcriptional activity at sampling point IV followed by a decrease at sampling point V.
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