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Surprisingly, analog 4 displayed relatively higher vasodepressor activity but significantly less potent colonic contractile activity than analog 5.
The enzyme displayed relatively higher affinity (lower Km) for 2-methylcyclohexanone but higher Vmax and kcat for phenylacetone as a result of which kcat/Km were similar for the two substrates.
The two-step assay displayed relatively higher S/Co ratios.
SC/D-F9 displayed relatively higher cytotoxicity compared to tamoxifen, paclitaxel, docetaxel and doxorubicin.
The parental cells displayed relatively higher NADH oxidation rate indicating robust complex I activity whereas NDUFS3 suppression systematically reduced mitochondrial complex I activity in shRNALow and shRNAhigh cells.
This strategy ensured for instance that populations which displayed relatively higher levels of variation were represented by more inbred lines (up to 8 inbred lines were extracted per population) than populations found to be monomorphic.
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Among them, Chlorella vulgaris FSP-E displayed relatively high cell growth rate and carbohydrate content.
In PARP enzyme assays using recombinant PARP-1 and PARP-2, quinazolinone derivatives displayed relatively high selectivity for PARP-1 and quinoxaline derivatives showed superior selectivity for PARP-2.
They displayed relatively high glass-transition temperatures (279 287 °C) and good thermal stability, with 10% weight-loss temperatures in excess of 522 °C in nitrogen and char yields at 800 °C in nitrogen higher than 67%.
In PARP enzyme assays using recombinant PARP-1 and PARP-2, the quinazolinone derivatives displayed relatively high selectivity for PARP-1 and quinoxaline derivatives showed superior selectivity for PARP-2, and the quinazolidinone derivatives did not have selectivity for PARP-1/2.
These methods generally displayed relatively high detection limits.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com