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We observe that most annotated and translated smORFs have conservation levels similar to canonical proteins and have so far displayed functionality in RNAi tests in some 50% of the cases.
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To display functionality beyond biosynthesis, we constructed a molecular communication 'device' (antibody binding Protein G QS complex) to target bacterial cells and demonstrated tailored QS responses among targeted bacteria.
Emerging reports indicate that in addition to coding regions, Helitrons also have captured and multiplied various host regulatory sequences that display functionality.
Database and display functionalities of DevInfo allow it to make a major contribution to such efforts.
The tissues remained viable for up to four weeks, and the system displayed biological functionality.
The doped hydrothermal carbons displayed similar functionality to the non-doped, although the effect of both heat treatment and activation was diminished.
Strikingly, 24 RNMs (11 nonsynonymous and 13 RNA mutations) and 67 SNMs (42 nonsynonymous, 25 RNA mutations) displayed comparable functionality values with those of disease-causing mutations.
The resulting cell line, cBAL111, displayed hepatic functionality similar to the parental cells prior to immortalization, and did not grow in soft agar.
Unlike McFAD2 and McFAD2v, the conjugase displayed mixed functionality; generating small amounts of 16:2 and 18 2 from Δ12 desaturase activity as well as eleostearic acid from conjugase activity with 18 2 (data not shown).
A mutant GLP-1R without this sequence was expressed in HEK293 cells (human embryonic kidney 293 cells) and displayed normal functionality with respect to ligand binding and activation of adenylate cyclase.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com