Sentence examples for displayed efficacy from inspiring English sources
In addition, the combination of the two classes of small molecules displayed efficacy in vivo against the recalcitrant T315I Bcr Abl mutant in a murine bone-marrow transplantation model.
We recently described a synthetic LXR inverse agonist that displayed efficacy in treatment of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD).
A case history is presented that describes the progression from a small compound or 'fragment' identified by nuclear magnetic resonance (NMR) as a relatively weak ligand of the GyrB protein of bacterial DNA gyrase to a derivative compound that displayed efficacy in an animal infection model and underwent phase 1 investigation in humans.
Four chemically unrelated CGRP receptor (CGRP-R) antagonists (olcegepant, telcagepant, MK-3207 and BI 44370 TA) have displayed efficacy in the treatment of migraine [192].
The radiolabeled peptide displayed efficacy against a range of different bacteria, including Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes.
It has also displayed efficacy in the prevention of postoperative thrombophlebitis [ 32], management of balance disorders of central origin, Parkinson's disease, Leukoaraiosis, and benign prostatic hyperplasia [ 3].
The present findings indicate β-lactamase inhibitors display efficacy, and mimic ceftriaxone activity, in an invertebrate anti-seizure screen.
Furthermore, incobotulinumtoxinA may display efficacy and tolerability in other indications.
Therefore, it is not surprising that gallium III) salts would also display efficacy against K. pneumoniae or have an effect on biofilm formation, as these previous studies and our unpublished data support the results reported herein.
However, a phase I trial in SLE patients failed to display efficacy of the intravenous and subcutaneous administration of recombinant human DNaseI, although its safety profile was acceptable [ 38].
However three large randomized controlled trials (RCTs) testing the efficacy of ONS for CM prevention, displayed modest efficacy, although the studies were criticized for poor methodological designs [10 12].
