Exact(5)
Off-speed might be an apt description of what the Nets displayed down the stretch.
Checkerboard assay results of p21 fibroblast-like synoviocytes (FLS) migration are presented such that dilutions of rheumatoid arthritis (RA) synovial fluids (SFs), which were included with the cells (in the lower wells), are displayed down the left hand column.
Of the top 30 highly expressed genes in sheep skin, all 9 keratin family members and keratin associated proteins displayed down regulation in black sheep skin, which was the same as observed in piebald Merino sheep skin [ 12].
Several proteins displayed the same expression difference (up-regulated or down regulated) in most of the time points for example peaks on the Q10 array at 5334 m/z displayed up regulation in diseased tissue at 90,120, 210, 240 and EP whilst 13642 and 14183 m/z displayed down regulation at the same time points.
This was seen in a study using the 3LL Lewis tumour model, which demonstrated that Treg cells exposed to paclitaxel displayed down regulation of Bcl-2 and upregulation of Bax, and upon blocking the Bcl-2 pathway, the ability of paclitaxel to ablate Treg cells compared to T effectors was impaired and both Treg and T effectors were affected.
Similar(55)
Of transcription factor related genes, 60 displayed down-regulation.
At mRNA level, transfected cells displayed down-regulation of MTDH, PDK1 and BCL-XL, while BAX and MAP3K1 were up-regulated.
Indeed, 1092 differentially expressed genes were detected in Group III (SaSbSc vs Sc) and 82.78% of these genes (904) displayed down-regulation, and accounted for the largest number in all the hybrids (Fig. 4a, Additional file 6: Table S2).
The fourth group was composed of AP2/ERF superfamily (ERF) genes, and five of the six genes, namely LOC_Os02g43790, LOC_Os04g46400, LOC_Os05g39590, LOC_Os08g42550, and LOC_Os09g35030, displayed down-regulation in Group III (Fig. 8d).
The cells, which displayed down-regulation of TAP-2, where subsequently used in the cytotoxicity assay (see experimental procedure above).
Four N-acetylated internal peptides from the proteins Vma22p, Sti1p, Fum1p and Srn2p, however, displayed down-regulation in the nat3Δ.
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