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During aging, quiescent NSCs displayed defects in their lysosomes, increased accumulation of protein aggregates, and reduced ability to activate.
This approach was originally used to assay a library of non-essential genes in S. pombe, enabling identification of scores of strains that displayed defects in splicing of two endogenous pre-mRNAs.
Moreover, gain-of-function mutants of Hh signaling displayed defects in body wall formation (Fig. 6F,J).
Moreover, both avian and mammalian myotubes displayed defects in sarcomere assembly, a specific trait of the fully differentiated phenotype.
The mutation in FLNB has displayed defects in skeletal and vascular development [26], but little is known about its function in colonocytes.
In addition, the skin of these mice appeared flaky and wrinkled by day 6 (Figure 1C) and displayed defects in pelage hair growth in addition to short and misshapen vibrissae (Figure 1D and 1E).
Similar(17)
Mammalian cells with defective HCF-1 also display defects in mitotic H3S10P status.
In addition, primary splenocytes display defects in TGF-beta-mediated repression of cytokine production.
Female ESR2-null mice (betaERKO) display defects in ovarian function and are subfertile.
To determine whether malignant cholangiocytes display defects in CD40 mediated apoptosis.
85 100% Ppt1RNAi-elav-Gal4 embryos display defects ranging from mild to severe axon bundles (Figure 5C and D; Table 4).
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