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Consistent with reduced binding, mutant p63 displayed a reduced ability to transactivate the Dsp enhancer region in H1299 cells when compared with wild-type p63.
Heavy media multitaskers also displayed a reduced ability to delay gratification in a delay discounting task.
As expected, Cdk5 KO mice displayed a reduced threshold for LTP induction (Figure 1B) [7].
Female Mc1re mice displayed a reduced response during both the first and second phase when compared to their littermate transgenic controls Tg-Mc1re (Figure 2B).
v225d CagA also displayed a reduced ability to induce the hummingbird phenotype than that of Western CagA.
Finally, MDA-MB-231 cells also displayed a reduced ability to heal a wound, following CD146 downmodulation.
MCPH1-deficient cells displayed a reduced mitotic arrest in response to spindle poisons, indicating impairment of the spindle checkpoint.
In line with such concepts, SCC-derived cell lines displayed a reduced ability to stratify on adhesive islands that was distinct from their ability to differentiate.
Also, an APL with two alanine substitutions at positions 265 and 270 (compound 23) displayed a reduced affinity comparable to the A3 peptide.
Chronicity of use was also associated with MMN alterations, as HLTs displayed a reduced duration and gap MMN vs. LSTs.
The coated foams displayed a reduced pressure drop compared to carbon granules and had good dynamic hexane vapour adsorption characteristics.
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