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Pulling apart the two helices up to 3.00 nm from each other, potentials of mean force were calculated by umbrella sampling with a view to compare the energy barriers of the mother dimer to the phage display variant.
Again, this individual did not display variant viruses within their viral population.
We propose that in cancer, a change in primary transcript expression at miRNA loci provides an important first step in the identification of those miRNAs that display variant epigenetic marks.
However, clonal regenerant animals display variant phenotypes caused by defective epigenetic reprogramming of gene expression [ 2], and clonal regenerant plants exhibit poorly understood heritable phenotypic ("somaclonal") variation [ 4 7].
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(2017) present multi-conformer analyses from room temperature X-ray data of two ubiquitin phage display variants binding deubiquitinase USP7.
These thieno[3,2-c]pyridin-4-amine derivatives displayed variant inhibitory activities against BTK in vitro.
In this paper, twenty one compounds displayed variant inhibitory activities against BTK in vitro, and compound 14g showed the most potent inhibitory activity against BTK enzyme, with the IC50 value of 12.8 nM.
Only a small number of probesets displayed variant expression between the bulk and LCM microarrays, while displaying consistent expression between the bulk and linear amplified bulk microarrays.
In addition, three loci, D13S317, D5S818, and D7S820, displayed variants adjacent to the core repeats and caused discordances between sequence-based and length-based typing results.
The only gene with more than two families displaying variants was KIAA0586, prompting further analysis.
Screening of a phage display Fc variant library identified mutations (e.g., M252Y/S254T/T256E termed YTE) with enhanced binding to human FcRn at pH 6.0 (Dall'Acqua et al., 2002).
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