Notably, AD samples displayed substantial variability in APP copies, revealing inherent limitations in precisely quantifying copy numbers in small, genomically mosaic cell populations and highlighting the necessity for single-cell analyses.
In summary, the results of the present study show that patients with systemic sclerosis display a substantial variability in the ventilatory response to hypercapnia.
In this work, we have shown that monoclonal cultures of E. coli infected by monoclonal viruses display a substantial variability in individual viral production, attaining up to an order of magnitude more variability than other bacterial phenotypic traits.
Despite these general relationships, people living within the same obesogenic environment display substantial between-person variability in body weight.
Unlike OCCs, though, the control samples display substantial changes and variability between time points; this is to be expected based on previous work indicating temporal changes in metabolism of OCSCs [ 10].
These loads show a substantial variability which has been statistically characterized.
Table 1 displays the characteristics of patients in the dataset at baseline assessment and shows that there is substantial variability across patients.
Since single cells display a largely heterogeneous, multi-component cytoskeleton architecture, it is little surprising that they are often characterized by a substantial variability that only represents the multiple realizations of their internal polymer scaffold.
Total median artemether maximum concentration (35.4 [range, 5.69 to 143] ng/ml) and exposure (104 [10.8 to 351] h · ng/ml) and dihydroartemisinin maximum concentration (83.0 [18.8 to 153] ng/ml) and exposure (200 [55.9 to 456] h · ng/ml) displayed substantial between-patient variability (Fig. 1).
The IPCC scientists reject this, reporting that while the warming trend is robust over decades, there is "substantial" variability within decades.
