Alternatively, the fact that OmcZ is displayed on the outer surface of the cell suggests that OmcZ in the extracellular matrix might make electron transfer among multiple OmcZ molecules a possible route for electron transfer through the biofilm.
Indeed, membrane-associated vimentin staining was also detected in non-permeabilized stromal cells (green "corona", Figure 4A), implying that some vimentin is displayed on the outer surface of the cell.
After purification of chimeric AP205-D2 VLPs by gel filtration to reliable purity confirmed by LDS-PAGE (Fig. S2), competitive ELISA showed that the D2 peptides are displayed on the outer VLP surface to the same extent as the Ang II peptide in the corresponding VLPs (not shown).
Again, it is possible that PS abnormally displayed on the outer surface of myelin fragments could be bound by CRT as part of a myelin debris clearance process.
The authors identify an allele of waaL that has a different specificity as it can now incorporate a peptidoglycan fragment that can be displayed on the outer membrane of E. coli.
Annexin-V, a 35 kDa calcium-dependent protein, binds with high affinity (K=10−9 M) specifically to PS residues that are displayed on the outer surface of apoptotic cells (Martin et al, 1995).
Considering functional roles for these intracellular granule membrane-expressed receptors, with their ligand-binding domains displayed on the outer granule membranes, these findings not only support extracellular granule function but also suggest that the granule-expressed receptors potentially serve as intracrine mediators of eosinophil-derived granule secretion.
Altered patterns of glycosylation are a universal feature of cancer with sialic acids – which are a group of unusual amino-modified acidic sugars ubiquitously displayed on the outer ends of mammalian glycan chains [ 1] – playing an especially prominent role as tumor-associated carbohydrate antigens (TACAs) [ 2, 3].
In this study, we designed a molecular structure to display GBP on the outer membrane of E. coli.
Apoptotic cells display phosphatidylserine on the outer side of the cell membrane, which serves as a signal for phagocytosis by macrophages [ 41].
