Exact(13)
Phage display methodology allowed selection of three phages that specifically bound to virulent Pb18.
In this study, we employed phage display methodology to screen for peptides that specifically recognize the target PKCδ as a novel biomarker for glioma.
In order to obtain a large-scale IR data set that covers the huge interactome space, we conducted a novel large-scale, automated in vitro experiment using an mRNA display methodology (Figure 1A).
Single-chain variable region Ab fragments were obtained from the RNA extracted from the hybridoma cells secreting mAb C7 (scFv C7) by using the phage display methodology, as described [3].
We investigated the potential of a display methodology for a cDNA library of maize young seedlings.
Using mRNA differential display methodology, they identified a novel p53-induced gene.
Similar(47)
Here, we demonstrate targeted detection of colonic dysplasia in vivo using a novel fluorescence-labeled peptide selected with phage display methodologies.
Interestingly, in an attempt to develop insulin mimetic peptides, the use of phage display methodologies led to the discovery of three groups of peptides unrelated in sequence to insulin that recognise three different sites on the IR surface [92].
This approach allowed the identification of a large number of cellulosomal module-containing proteins and produced a rumen microbial metasecretome display library that is currently being used to explore the roles of rumen bacterial cellulosomes and other CAZymes via standard phage display affinity selection and protein display methodologies.
TCR tetramers [ 70] and pMHC display methodologies [ 71- 74] have not gained widespread use for antigen discovery, and they tend to be hampered by a combination of low solubility and binding affinity issues, as well as the difficult logistics of large-scale screens.
The Alu element PCR-display methodology and Alu-specific primers described by Xing et al [ 28] were used for identifying species-specific Alu insertions.
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