Compared with these bacteria, those grown in space displayed major changes in the activity of 167 genes and in the production of 73 proteins.
Of particular interest in this previous study [ 26] was the observation that the cells were not only growth inhibited in response to mifepristone, but that they also displayed major changes in their morphological features.
In a previous study we made the serendipitous observation that when cancer cells of various tissues of origin were exposed to concentrations of mifepristone that inhibited their growth [ 26], the cells displayed major changes in shape when compared to untreated growing cells.
Therefore, the invading AMA1 mutant parasites display no major changes in MJ architecture because the parasite uses paralogs of the generic AMA1 RON2 pair as substitutes.
However, embryos deficient for Ptena and Ptenb die at 5 6 days post-fertilization (dpf) and display major hyperplastic-dysplastic changes in several organs.
However, scientific opinion articles displayed major temporal changes in the positive-to-negative effect ratio following regulatory warnings, showing more negative-effect articles.
Classically these metabolites are identified by either mutant screens or looking for metabolites which display a major change in concentration.
The fossil diatom and geochemical sediment analyses display three phases that represent major changes in the lake development: (i) a marshy phase (ca. 16.6 10 cal. kyr BP); (ii) a brackish water lagoon phase (ca. 10 6.6 cal. kyr BP); and (iii) a freshwater lake phase (since ca. 6.6 cal. kyr BP).
