Sentence examples for display efficacy from inspiring English sources

The molecules exhibit excellent selectivity and display efficacy in a SOD1 mutant mouse model of ALS.

The present findings indicate β-lactamase inhibitors display efficacy, and mimic ceftriaxone activity, in an invertebrate anti-seizure screen.

Furthermore, incobotulinumtoxinA may display efficacy and tolerability in other indications.

However, a phase I trial in SLE patients failed to display efficacy of the intravenous and subcutaneous administration of recombinant human DNaseI, although its safety profile was acceptable [ 38].

Therefore, it is not surprising that gallium III) salts would also display efficacy against K. pneumoniae or have an effect on biofilm formation, as these previous studies and our unpublished data support the results reported herein.

Compound 5x displays efficacy in human tumor xenograft models.

Compound 32 displays efficacy in human tumour animal xenograft model.

In addition, the combination of the two classes of small molecules displayed efficacy in vivo against the recalcitrant T315I Bcr Abl mutant in a murine bone-marrow transplantation model.

We recently described a synthetic LXR inverse agonist that displayed efficacy in treatment of hepatic steatosis in a mouse model of non-alcoholic fatty liver disease (NAFLD).

A case history is presented that describes the progression from a small compound or 'fragment' identified by nuclear magnetic resonance (NMR) as a relatively weak ligand of the GyrB protein of bacterial DNA gyrase to a derivative compound that displayed efficacy in an animal infection model and underwent phase 1 investigation in humans.

Four chemically unrelated CGRP receptor (CGRP-R) antagonists (olcegepant, telcagepant, MK-3207 and BI 44370 TA) have displayed efficacy in the treatment of migraine [192].