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Alternatively, cell lines derived from carcinogen-treated animals have extended proliferative capacity but do not display differentiated characteristics [ 11].
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Instead, the schizophrenia organoids displayed differentiated Pan-Neu+ Pan-Neu+deep withineuronsZ andeep regions.
Melanoma inhibitory activity/cartilage-derived retinoic acid-sensitive protein (MIA/CD-RAP) was cloned as a secreted protein from human melanoma cell lines and independently identified by differential display comparing differentiated with dedifferentiated chondrocytes.
It is of particular interest to note that T cell responses restricted by HLA alleles associated with HIV-1 long-term nonprogression such as HLA-B27 or HLA-B57 epitopes did not uniformly display terminally differentiated maturation status.
Newly primed T cells are phenotypically distinct from exhausted T cells and display less differentiated phenotype characterized by higher expression of CD62L, CD27, anti-apoptotic protein bcl-2 and cytokines such as TNF-α and IL-2.
These differences display partly differentiated functional organizations of vocal controlling pathways for communication calls and echolocation calls below PAG level.
The reduction in the proportion of cells displaying elongated aggregates at later time points reflected an increase in cells displaying a differentiated phenotype in addition to an increase in an apoptotic appearance (data not shown).
In case of development and differentiation, differentiated cells display a stable, cell-type-specific methylation pattern, permanently switching off the expression of genes that are not essential for the respective cell type.
Cells within fused tissue displayed a differentiated phenotype with rounded morphology, close to chondrocytes.
However, the majority of the Mbd3 shRNA cells displayed marked differentiated morphology when compared to control shRNA cells.
Resveratrol-exposed female rats displayed more differentiated lobular structures and decreased proliferation in the mammary terminal ductal structures, making them less vulnerable to damage by carcinogens (Whitsett et al. 2006).
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