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Mammalian cells with defective HCF-1 also display defects in mitotic H3S10P status.
We also find that follicle cells defective in Hippo signaling accumulate the Notch receptor and display defects in endocytosis markers.
Of course in so doing we have again to use ordinary words, and these may display defects similar to those which the elucidations are intended to remove.
This is consistent with the observation that human Pax6 homozygote mutations display defects in non-eye regions such as nose, forebrain, hindbrain and pancreas (Hill et al., 1991; St-Onge et al., 1997).
Both ether lipid-deficient mouse models and human patients with ether lipid deficiency often display defects in myelination in both the central and peripheral nervous systems (da Silva et al., 2012).
To determine whether malignant cholangiocytes display defects in CD40 mediated apoptosis.
Some mouse embryos heterozygous for a Bmp4 loss-of-function mutation display defects in ureteric stalk elongation [21].
These γCOP mutant embryos display defects in the formation of the embryonic cuticle; denticles are barely made.
Moreover, the Dmrt2b morphants display defects in heart and visceral organ asymmetry, and, some lateral-plate mesoderm (LPM) markers expressed in left side are randomized.
In contrast, zebrafish ednrb1/rose mutants display defects in subsets of adult melanophores and iridiphores but lack an embryonic chromatophore phenotype [37].
85 100% Ppt1RNAi-elav-Gal4 embryos display defects ranging from mild to severe axon bundles (Figure 5C and D; Table 4).
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