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Snrk knockout (KO) mice display enlarged hearts, and die at postnatal day 0. Microarray analysis of embryonic day 17.5 Snrk hearts, and blood profile of neonates display defect in lipid metabolic pathways.
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Mammalian cells with defective HCF-1 also display defects in mitotic H3S10P status.
We also find that follicle cells defective in Hippo signaling accumulate the Notch receptor and display defects in endocytosis markers.
In addition, primary splenocytes display defects in TGF-beta-mediated repression of cytokine production.
Female ESR2-null mice (betaERKO) display defects in ovarian function and are subfertile.
Of course in so doing we have again to use ordinary words, and these may display defects similar to those which the elucidations are intended to remove.
To determine whether malignant cholangiocytes display defects in CD40 mediated apoptosis.
Some mouse embryos heterozygous for a Bmp4 loss-of-function mutation display defects in ureteric stalk elongation [21].
85 100% Ppt1RNAi-elav-Gal4 embryos display defects ranging from mild to severe axon bundles (Figure 5C and D; Table 4).
These γCOP mutant embryos display defects in the formation of the embryonic cuticle; denticles are barely made.
Moreover, the Dmrt2b morphants display defects in heart and visceral organ asymmetry, and, some lateral-plate mesoderm (LPM) markers expressed in left side are randomized.
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