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In other words, beads that are scored as hits often display compounds that prove to be poor ligands for the target of interest when they are resynthesized and carried through validation trials.
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Compounds annotated on the human cyclooxygenases (annotated with a star in the plots) display compound similarity distributions with mean values skewed towards 1.
The broad spectra of activity across the preclinical seizure models in mice (ip) displayed compounds 4, 5, 11, and 19.
The broad spectra of activity across the preclinical seizure models displayed compounds 4, 7, 8, 13, 15 18, 24, and 26.
These enzymes are potentially very useful for the synthesis of carbohydrate displaying compounds.
Although the two DNA encoding sequences were very different and easily distinguished, the QC beads displayed compounds with mass redundancy at Pos3, which would have confounded MS/MS-based sequencing.
Analysis of the binding conformation of 42 in active site displayed compound 42 was stabilized by hydrogen bonding interactions with Lys822, which was different from other derivatives.
Two (9%) individuals displayed compound heterozygous mutations in the USH2A gene, which is a higher frequency rate compared to that of a previous study reporting 11% of GJB2 mutation negative children with HL carrying single Usher syndrome mutations.
Fluorescent spectrum displays that compounds 1 and 2 are potential luminescent materials.
This chapter describes a versatile chemical approach for displaying target compounds on the bacterial cell wall.
The North Italian populations displayed specific compounds hexadecenal and hexadecanal.
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