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LAMA5-null mice die in utero with multiple malformations; hypomorphic animals display anomalies such as renal and pulmonary malformations (Nguyen et al., 2002; Shannon et al., 2006).
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These maps display anomaly values of forecast 2-meter temperature, sea surface temperature, and precipitation at multiple leads and start times during the year for a selection of climate models.
During the data analysis, we observed a number of tags displaying anomalies such as spikes in their activity records.
Nevertheless, the most severe mutants display cardiac anomalies comparable to the heart defects seen in tbx3b morphant embryos.
In addition, most patients carrying mutations in NHEJ genes display developmental anomalies which are likely the result of a general defect in repair of endogenously induced DSBs such as those arising during normal DNA replication.
Eutopic and ectopic endometria of endometriosis patients display distinct anomalies in levels of expression of prostaglandins receptivity and uptake factors.
Interestingly, the Klk4 ablated mice display rod/interod anomalies besides enamel maturation defects (27).
We have previously shown that WASP−/− DCs display equivalent anomalies in β2-integrin clustering [10] and focal contact formation to that observed in WIP−/− DCs [11].
ARM phenotypes are also partly included in several diseases, such as Currarino syndromes, Townes Brocks Syndromes and VACTERL complex, and these patients display other anomalies including anal fistula, sacral malformations and renal malformations.
Mice lacking fibulin-1 die perinatally and display vascular anomalies in the kidney in addition to extensive hemorrhage in several organs, likely related to abnormalities in endothelial cell interactions with subendothelial ECM [ 14].
U3 and U4 displayed significant anomalies in Tibet and North America, respectively.
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